Cov txiv hmab txiv ntoo twg ua rau tus kws kho hniav deb?

Cov txiv hmab txiv ntoo ua lub luag haujlwm tsis sib haum xeeb rau peb cov hniav - lawv yog ob qho tib si saib xyuas thiab muaj peev xwm invaders. Raws li ib tug tswv cuab ntawm lubtxiv apple extractkev lag luam, peb yuav tsum tau delve rau hauv qib molecular los tshawb xyuas cov khoom tshwj xeeb hauv cov txiv hmab txiv ntoo uas ua haujlwm, thiab lawv cov txheej txheem ntawm kev ua haujlwm yog dab tsi.

Tsuas yog categorizing qhov cuam tshuam ntawm cov txiv hmab txiv ntoo ntawm cov hniav raws li "zoo" lossis "phem" yog ib qho -sab. Qhov tseeb, thaum peb zom ib daimkua txiv, ib tug complex biochemical kev ua si yog nthuav tawm nyob rau hauv peb lub qhov ncauj.

• Qhov zoo: lub qhov ncauj huv huv.'

Kev ntxuav lub cev thiab qaub ncaug secretion:

① zom txiv hmab txiv ntoo nyiamtxiv applesuas yog nplua nuj nyob rau hauv fiber ntau thiab muaj ib tug crisp kev ntxhib los mos yog nws tus kheej ib tug neeg kho tshuab tu txheej txheem. Thaum cov nqaij fibers rub tawm ntawm cov hniav, lawv tuaj yeem pab tshem tawm qee cov khoom noj uas muaj nyob hauv cov khoom noj thiab cov quav hniav.

②Qhov tseem ceeb tshaj, zom zom tuaj yeem ua rau cov qog ua kua qaub thiab tso cov qaub ncaug ntau. Cov qaub ncaug yog lub ntuj "regulator" ntawm qhov ncauj ib puag ncig. Nws tsis tsuas yog ntxuav tawm cov zaub mov seem xwb tab sis kuj muaj cov kab mob buffering uas tuaj yeem ua rau cov kua qaub uas ua los ntawm cov quav hniav. Cov ntxhia ions, xws li calcium thiab phosphorus, nyob rau hauv cov qaub ncaug yog qhov tsim nyog rau kev tshem tawm thaum ntxov thiab remineralization ntawm enamel, uas yog qhov tseem ceeb rau kev tswj cov hniav hardness.

• Sab tsis zoo: Muaj peev xwm hem ntawm Qab Zib thiab Acid

① Qab Zib - "lub zog qws" ntawm cov kab mob cariogenic:

Fructose, sucrose, thiab lwm yam piam thaj hauv cov txiv hmab txiv ntoo yog "delicacies" ntawm cov kab mob xws li Streptococcus mutans, cov kab mob cariogenic tseem ceeb hauv qhov ncauj. Tom qab metabolizing qab zib, cov kab mob no tsim cov tshuaj acidic, feem ntau lactic acid, uas ua rau txo qis pH nqi ntawm qhov ncauj ib puag ncig.
②Acid corrosion - tus "corrosive agent" ntawm enamel: Thaum pH tus nqi ntawm lub qhov ncauj kab noj hniav qis dua tus nqi tseem ceeb ntawm 5.5, cov txheej tiv thaiv nyuaj tshaj plaws ntawm cov hniav - enamel - yuav pib demineralize, uas yog, calcium thiab phosphorus ions yuav ploj. Citrus txiv hmab txiv ntoo, txiv pos nphuab, thiab qee hom txiv apples lawv tus kheej muaj cov organic acids siab xws li citric acid thiab malic acid, uas tuaj yeem cuam tshuam cov hniav enamel thiab ua rau "Dental Erosion."

Cov kev tshawb fawb niaj hnub no tau pom tias cov txiaj ntsig tseem ceeb ntawm cov txiv hmab txiv ntoo rau kev noj qab haus huv ntawm qhov ncauj nyob hauv lawv cov nplua nuj ntawm ntau yam bioactive compounds, tshwj xeeb tshaj yogpolyphenolsthiabflavonoids. Cov tshuaj no yog precisely lub tsom xam ntawm cov xim nyob rau hauv cov nroj tsuag extract kev lag luam.

• Core mechanism 1: Inhibit thiab disintegrate lub biofilm ntawm cov kab mob cariogenic

Qhov tshwm sim ntawm cov kab mob hniav tsis yog tshwm sim los ntawm ib tus kab mob, tab sis yog los ntawm "biofilm" tsim los ntawm kev sib sau ntawm ntau yam kab mob, xws li Streptococcus mutans, feem ntau hu ua cov quav hniav. Cov qauv biofilm no yog tawv tawv, muaj peev xwm tiv taus sab nraud lub cev thiab tshuaj lom neeg, thiab tsis tu ncua ua kua qaub.PolyphenolicCov tshuaj muaj peev xwm inhibit qhov kev loj hlob, acid ntau lawm, thiab adhesion ntawm Streptococcus mutans ntawm cov hniav. Lawv lub hom phiaj yog qhov tseeb heev, piv txwv li:

①Inhibition ntawm cov enzyme tseem ceeb: cuam tshuam nrog cov enzymes tseem ceeb koom nrog hauv cov kab mob qab zib metabolism (xws li glycosyltransferases), txo cov kua qaub ntawm qhov chaw.
②Blocking kev taw qhia txoj hauv kev: cuam tshuam rau pawg pawg-sensing system ntawm cov kab mob, tiv thaiv lawv los ntawm kev sib sau ua ke los tsim cov biofilm muaj zog.
③ Hloov cov yam ntxwv ntawm cov kab mob: txo lawv cov hydrophobicity, ua rau nws nyuaj rau lawv ua raws li cov enamel nto.

Nyob rau hauv xyoo tas los no, kev lag luam loj ntawm Tuam Tshoj tuscog extractkev lag luam tau txuas ntxiv mus tsis tu ncua. Nrog kev nthuav dav txuas ntxiv ntawm thaj chaw hauv qab, tshwj xeeb tshaj yog nyob rau hauv kev noj qab haus huv, khoom noj khoom haus, thiab kev saib xyuas tus kheej, kev lag luam kev cia siab yog qhov zoo heev.
Cov khoom siv kho qhov ncauj yog qhov zoo tshaj plaws daim ntawv thov scenario nyob rau hauv cov qauv no.

• Cov tshuaj txhuam hniav muaj nuj nqi: ntxiv nrogtxiv apple anthocyanin extract, tshwj xeeb yog tsim los inhibit plaque adhesion.
• Herbal mouthwash: nplua nuj nyob rau hauvpolyphenolsmuab rho tawm los ntawm txiv apples, nws muaj peev xwm ua tau zoo neutralize lub qhov ncauj tsw, inhibit cov kab mob phem, thiab muaj ib tug me me thiab tsis muaj - ua rau khaus saj.

Kev kho hniav lozenges los yog zom cov pos hniav: infused nrog flavonoids xws li baicalein, muab kev tiv thaiv txuas ntxiv rau cov hniav hniav thaum nws txaus siab rau nws cov deliciousness.

Yog xav paub ntxiv txogtxiv apples polyphenols, txuas nrog Serrisha los ntawm APPCHEM. (Email:cwj@appchem.cn; +86-138-0919-0407)

Kev siv

[1]R. Shellis, J. Featherstone et al. "Kev nkag siab txog chemistry ntawm kev kho hniav erosion." Monographs hauv qhov ncauj science (2014). [2014]
[2] HJ Florestano. "Kev tshawb fawb txog kev noj qab haus huv ntawm qhov ncauj raws li pom hauv cov qaub ncaug, nrog rau kev siv tshwj xeeb rau hauv zos thiab kev siv cov txiv hmab txiv ntoo citrus, cov kab mob hauv qhov ncauj aciduric, kev ua diastatic thiab pH." (1940) [1940]

[3] S. Duarte, S. Grégoire et al. "Inhibitory teebmeem ntawm cranberry polyphenols ntawm kev tsim thiab acidogenicity ntawm Streptococcus mutans biofilms.." FEMS Microbiology Letters.[2006-04-01]

[4] Lucille Rudin, M. Bornstein et al. "Inhibition ntawm biofilm tsim thiab virulence yam ntawm cariogenic qhov ncauj kab mob Streptococcus mutans los ntawm ntuj flavonoid phloretin." Phau ntawv Journal of Oral Microbiology. [2023-07-03]