Nyob rau hauv lub ntiaj teb no cog extract ua lag luam,ntsuab tshuaj yej extractthiabgrape noob extracttau ntev tau suav tias yog ob lub ntsiab lus tseem ceeb hauv thaj chaw ntawm cov tshuaj tua kab mob antioxidant, nrhiav kev siv dav hauv cov khoom noj khoom haus, khoom noj khoom haus, khoom noj khoom haus kom zoo nkauj, thiab tshuaj- cov khoom muaj feem xyuam. Txawm hais tias ob qho tib si muaj npe nrov rau lawv "siab antioxidant muaj peev xwm," qhov sib txawv tseem ceeb muaj nyob nruab nrab ntawm lawv nyob rau hauv cov nqe lus ntawm antioxidant mechanisms, nyob rau hauv vitro thiab nyob rau hauv vivo kev ua si, daim ntawv qhia cov lus qhia, kev ruaj ntseg profiles, thiab kev lag luam qauv. Rau cov neeg ua haujlwm tshaj lij thiab cov neeg tsim khoom tsim khoom, kev nkag siab txog cov kev sib txawv no muaj qhov tseem ceeb tshaj qhov tseem ceeb tshaj qhov tsuas yog muab piv rau lawv cov txheeb ze antioxidant potency.
Yuav Ua Li Cas Antioxidant Mechanisms thiab ORAC Qhov Tseem Ceeb Sib piv?
Los ntawm cov tshuaj tiv thaiv kab mob antioxidant,ntsuab tshuaj yej extractthiabgrape noob extracttsis txhob siv lawv cov teebmeem los ntawm txoj kev zoo ib yam nkaus.
- Lub ntsiab active tivthaiv ntawmntsuab tshuaj yej extractyog tshuaj yej polyphenols, sawv cev feem ntau los ntawm epigallocatechin gallate (EGCG). Raws li kev tshawb fawb xyoo 2022 hauv Phau Tsom Faj Txog Kev Ua Liaj Ua Teb thiab Khoom Noj Khoom Noj, EGCG muaj lub peev xwm ua kom dawb radical scavenging muaj peev xwm thiab tuaj yeem txhawb kev nthuav tawm ntawm cov enzymes antioxidant (xws li SOD thiab CAT) hauv lub cev los ntawm kev tswj hwm Nrf2 txoj kev taw qhia. Nws cov tshuaj tiv thaiv antioxidant yog li nthuav tawm ob tus yam ntxwv ntawm ob qho tib si "ncaj qha scavenging" thiab "endogenous regulation".
- Cov ntsiab lus tseem ceeb ntawmgrape noob extractyogProanthocyanidins (OPCs), belongs rau chav kawm ntawm oligomeric lossis polymeric flavanols. Cov ntaub ntawv luam tawm hauv Food Chemistry hauv 2021 qhia tiasTxiv hmab txiv ntoo OPCsnthuav tawm tshwj xeeb tshaj yog siab radical scavenging muaj peev xwm nyob rau hauv vitro qauv, qhia tshwj xeeb tshaj yog tseem ceeb clearance cuam tshuam tawm tsam hydroxyl radicals thiab peroxy radicals. Hais txog ORAC (Oxygen Radical Absorbance Capacity) qhov tseem ceeb, ntau qhov kev tshawb fawb qhia tias cov noob txiv hmab txiv ntoo feem ntau pom muaj txiaj ntsig ORAC siab dua li cov tshuaj yej ntsuab. Txawm li cas los xij, qhov kev ntsuas no feem ntau cuam tshuam rau hauv vitro antioxidant muaj peev xwm thiab tsis zoo sib npaug rau hauv vivo bioavailability.
Yog li ntawd, los ntawm kev xav txog kev siv tshuab, tshuaj yej ntsuab extract nyhav rau kev tswj hwm kev tiv thaiv kab mob antioxidant, thaum cov noob txiv hmab txiv ntoo extract ua tau zoo nyob rau hauv siab - siv cov dawb radical scavenging muaj peev xwm.
Lawv txawv li cas ntawm daim tawv nqaij noj qab haus huv thiab kev tiv thaiv kev laus -Cov txiaj ntsig kev laus?
Hauv thaj chaw ntawm daim tawv nqaij noj qab haus huv thiab tiv thaiv -aging, ob qho tib sintsuab tshuaj yej extractthiabgrape noob extracttau kawm ntau heev, txawm hais tias lawv lub hom phiaj tseem ceeb sib txawv.
- Lub ntsiab kom zoo dua ntawmntsuab tshuaj yej extracthauv daim ntawv thov kev tu tawv nqaij nyob hauv nws cov tshuaj tiv thaiv - mob thiab tiv thaiv - cov khoom siv yees duab. Raws li kev tshawb fawb xyoo 2020 hauv Kev Tshawb Fawb Kev Tshawb Fawb, EGCG inhibits kev tso tawm ntawm UV-induced inflammatory mediators thiab txo cov kev qhia ntawm matrix metalloproteinases (MMPs) cuam tshuam nrog collagen degradation. Yog li ntawd, nws tuav lub luag haujlwm tseem ceeb hauv kev tshaj tawm - kev kho tshav ntuj thiab tiv thaiv - cov qauv kev yees duab.
- Grape noob extractQhov zoo ntawm daim tawv nqaij tiv thaiv- kev laus tshwm sim feem ntau los ntawm kev tiv thaiv collagen thiab kev txhim kho microcirculation. Ib txoj kev tshawb fawb 2021 hauv International Journal of Cosmetic Science qhia tiasTxiv hmab txiv ntoo OPCstxhim kho daim tawv nqaij firmness thiab elasticity los ntawm bolstering capillary elasticity thiab mitigating oxidative kev nyuaj siab puas tsuaj rau lub dermis. Qhov no tsim kom muaj lub hauv paus tsim nyog rau cov khoom noj kom zoo nkauj ntawm qhov ncauj, tiv thaiv - cov qauv kev laus, thiab cov khoom noj qab haus huv ntawm daim tawv nqaij.
Los ntawm qhov kev xav ntawm kev tsim khoom,ntsuab tshuaj yej extractyog qhov zoo dua rau kev hais txog "tiv thaiv- mob, tiv thaiv tawv nqaij txhawb nqa", thaumgrape noob extractyog feem ntau ua hauj lwm rau "cov qauv tiv thaiv-aging thiab tawv elasticity txhawb".
Dab tsi yog Qhov Kev Nyab Xeeb Profiles thiab Cov Teeb Meem Muaj Teeb Meem?
Hais txog kev nyab xeeb, ob qho tib sintsuab tshuaj yej extractthiabgrape noob extractmuaj keeb kwm ntev ntawm kev siv nyab xeeb, txawm tias lawv cov kev pheej hmoo profile tsis zoo ib yam nkaus.
- Kev nyab xeeb kev txhawj xeeb txogntsuab tshuaj yej extractFeem ntau yog nyob rau ntawm lub siab kam rau siab ntawm cov koob tshuaj EGCG. Raws li 2018 kev pom zoo los ntawm European Food Safety Authority (EFSA), thaum noj EGCG txhua hnub ntau dua 800 mg, qhov hloov pauv hauv daim siab ua haujlwm yuav tshwm sim hauv qee tus neeg rhiab heev. Yog li ntawd, kev siv tshuaj nruj nruj thiab cov lus qhia meej txog kev siv yuav tsum tau muaj nyob rau hauv cov khoom noj.
- Piv txwv li,grape noob extractpom zoo tolerability nyob rau hauv cov pa ntau npaum li cas. Kev soj ntsuam kev nyab xeeb xyoo 2021 hauv Regulatory Toxicology thiab Pharmacology tau qhia tias ntev - ntxiv nrog rau cov noob txiv hmab txiv ntoo OPCs tsis pom muaj qhov cuam tshuam loj rau hepatotoxicity lossis kev cuam tshuam hauv lub cev. Txawm li cas los xij, nws tuaj yeem muaj cov tshuaj tiv thaiv kab mob me me, yuav tsum tau soj ntsuam xyuas kom zoo thaum siv nrog cov tshuaj anticoagulant.
Rau kev yuav khoom B2B,ntsuab tshuaj yej extractyuav tsum tau ua kom pom tseeb ntau dua rau cov qib standardization thiab ntau npaum li cas tsim, whereasgrape noob extractQhov chaw tseem ceeb dua rau proanthocyanidin purity thiab impurity tswj.
Xaus: Yuav ua li cas cov neeg yuav khoom xaiv ntawm Green Tea thiab Grape Seed Extracts?
Hauv cov ntsiab lus,ntsuab tshuaj yej extractthiabgrape noob extracttsis tsuas yog sib tw rau lub npe ntawm 'antioxidant champion', tab sis yog sawv cev rau cov kev ua haujlwm sib txawv thiab kev siv logics. Ntsuab tshuaj yej extract yog zoo- haum rau cov khoom kab hais txog kev tiv thaiv kab mob antioxidant, kev tswj cov metabolism, thiab tiv thaiv - tiv thaiv kab mob. Hloov pauv,grape noob extractUa kom pom kev ua tau zoo dua hauv siab - siv tshuaj tua kab mob antioxidant, tawv nqaij tiv thaiv - laus, thiab mob plawv. Rau cov neeg ua haujlwm tshaj lij thiab R&D cov neeg ua haujlwm, qhia meej meej txog cov khoom lag luam qhov chaw ua haujlwm feem ntau tuav kev txiav txim siab ntau dua - ua kom muaj nuj nqis dua li tsuas yog muab piv rau ORAC qhov tseem ceeb.
Yog xav paub ntxiv txogcov ntaub ntawv khoom, txuas nrog Serrisha los ntawm APPCHEM. (Email:cwj@appchem.cn; +86-138-0919-0407)
Kev siv
[1] C. Manach, A., Scalbert et al. "Polyphenols: cov khoom noj thiab bioavailability." American Journal of Clinical Nutrition (2004).
[2] Muhammad Modassar Ali Nawaz Ranjha. "Ib qho kev tshuaj xyuas tseem ceeb ntawm kev muaj Polyphenols hauv kev lag luam ntau yam ntawm Apple Peel, lawv cov txiaj ntsig thiab kev noj qab haus huv." (2020).
[3]Nelly Medina-Torres, T. Ayora-Talavera et al. "Ultrasound- pab tshem tawm rau kev rov qab los ntawm phenolic tebchaw los ntawm cov zaub mov." Agronomy (2017).