Curcumin vs Resveratrol: Qhov twg Polyphenol xa cov txiaj ntsig zoo dua?

Ntawm cov natural polyphenolic active compounds,curcuminthiab resveratroltau ntev commanded tseem ceeb. Ob leeg tau tshawb fawb ntau thiab siv rau hauv cov khoom lag luam tsom antioxidant, tiv thaiv- mob, mob plawv, thiab tiv thaiv- cov txiaj ntsig kev laus. Txawm li cas los xij, los ntawm kev pom ntawm cov qauv tshuaj, cov txheej txheem ntawm kev ua, bioavailability, kev nyab xeeb, thiab kev lag luam kev siv logic,curcuminthiabresveratroltsis ncaj qha interchangeable raw khoom. Rau cov kws tshaj lij kev muag khoom thiab cov neeg ua haujlwm txhim kho cov khoom lag luam, kev nkag siab txog lawv qhov sib txawv pab txhawb kev xaiv cov khoom muaj txiaj ntsig ntau dua thaum lub sijhawm ua haujlwm thiab cov qauv tsim khoom.

Txawm tiascurcuminthiabresveratrolob leeg koom nrog hauv chav kawm ntawm polyphenolic tebchaw, lawv cov qauv molecular thiab lub hom phiaj muaj qhov sib txawv tseem ceeb.

• Curcumin, diarylheptane compound muab rho tawm los ntawm rhizome ntawm turmeric (Curcuma longa), concentrates nws lub luag haujlwm tseem ceeb ntawm kev tswj hwm kev tiv thaiv - inflammatory pathways. Raws li kev tshawb fawb xyoo 2021 hauv Biochemical Pharmacology,curcuminNws txo qis qhov mob ntev los ntawm inhibiting inflammatory signaling pathways xws li NF-κB, COX-2, thiab TNF- . Nws cov teebmeem antioxidant feem ntau tshwm sim los ntawm "txhaum cov hauv paus hniav ua rau oxidative kev nyuaj siab" es tsis yog tsuas yog tshem tawm cov dawb radicals.

• Resveratrolyog ib tug diphenyl ethylene polyphenol ib txwm tshwm sim nyob rau hauv txiv hmab txiv ntoo tawv, Polygonum cuspidatum, thiab lwm yam nroj tsuag. Raws li 2022 Phau ntawv Journal of Nutritional Biochemistry txoj kev tshawb fawb, resveratrol koom nrog hauv cellular zog metabolism thiab mitochondrial kev tswj hwm los ntawm kev ua kom SIRT1 thiab AMPK txoj hauv kev. Nws cov tshuaj tiv thaiv antioxidant leans ntau dua rau ncua kev laus ntawm cellular thiab tswj cov metabolic homeostasis.

Yog li ntawd, los ntawm ib tug mechanistic foundations,curcuminnthuav tawm ntau dua ntawm "mob- tswj hom antioxidant", thaumresveratrolleans mus rau "metabolic thiab laus- tswj hom antioxidant".

Nyob rau hauv cov ntsiab lus ntawm kev cuam tshuam kab mob ntev thiab tiv thaiv - daim ntawv thov kev laus,curcuminthiabresveratrolnthuav qhia qhov ua haujlwm tau zoo.

• Curcuminmuaj ib tug kuj zoo -tsim daim ntawv thov lub hauv paus nyob rau hauv lub domains ntawm kev noj qab haus huv kev sib koom tes, o- ntsig txog metabolic ntshawv siab, thiab plab noj qab haus huv. Ib xyoo 2020 kev tshuaj xyuas hauv Phytotherapy Research qhia tias curcumin muab cov txiaj ntsig zoo sib xws hauv kev txo cov mob osteoarthritis thiab txo cov cim inflammatory, ua rau nws tshwj xeeb tshaj yog tsim rau cov khoom lag luam nyob rau hauv "kev tswj xyuas mob ntev".
• ResveratrolPiv txwv li, feem ntau cuam tshuam nrog kev noj qab haus huv ntawm cov hlab plawv, cov kab mob metabolic, thiab kev tshawb fawb los tiv thaiv kev laus -. Kev tshawb fawb xyoo 2023 hauv Nutrients tau qhia txog resveratrol cov txiaj ntsig zoo ntawm kev txhim kho insulin rhiab heev, vascular endothelial kev ua haujlwm, thiab oxidative kev ntxhov siab, ua kom nws cov lus piav qhia zoo dua nrog "kev tshawb fawb ntev" thiab "kev noj qab haus huv ntawm tes".

Yog li ntawd, nyob rau hauv kev siv,curcuminnyiam mus rau cov khoom uas muaj kev qhia meej meej ua haujlwm thiab cov tsos mob -kev taw qhia, thaumresveratrolyog qhov zoo dua rau kev tswj hwm kev noj qab haus huv thiab tiv thaiv -cov khoom lag luam kev laus.

Bioavailability sawv cev rau qhov kev sib tw tseem ceeb rau ob qho tib si curcumin thiab resveratrol.

• Curcuminnws tus kheej nthuav tawm cov dej tsis zoo solubility thiab cov metabolism sai, ua rau qis hauv vivo absorption tus nqi rau cov qauv formulations. Raws li 2021 cov ntaub ntawv los ntawm Molecular Nutrition & Food Research, unmodified curcumin qhia tau tias tsis tshua muaj qhov ncauj bioavailability. Yog li ntawd, kev lag luam kev daws teeb meem feem ntau siv piperine co-formulation, nanotechnology, los yog phospholipid complexes los txhim kho kev nqus tau zoo.
• ResveratrolZoo sib xws ntsib teeb meem metabolism sai, txawm tias nws qhov me me molecular tso cai kom nqus tau sai. Ib txoj kev tshawb fawb 2022 hauv Clinical Nutrition qhia tias resveratrol hloov pauv sai sai rau glucuronic acid conjugates hauv vivo, txwv nws lub sijhawm ua haujlwm. Yog li ntawd, cov khoom tsim feem ntau xav tau kev tsim los yog cov tswv yim sib xyaw kom ntev nws qhov kev kho mob.

Hais txog kev nyab xeeb, ob lub tebchaw feem ntau muaj kev nyab xeeb nyob rau hauv qhov tsim nyog ntau npaum li cas. European Food Safety Authority (EFSA) sau tseg tiascurcuminqhia tau tias muaj kev nyab xeeb zoo hauv cov khoom noj, txawm hais tias tus neeg muaj kev hloov pauv tau lees paub rau kev siv siab - koob, ntev - siv sijhawm.ResveratrolTej zaum yuav ua rau mob plab me me ntawm cov koob tshuaj siab, yuav tsum tau ua tib zoo soj ntsuam rau cov tib neeg noj cov tshuaj anticoagulant.

Los ntawm kev lag luam thoob ntiaj teb kev xav, kev lag luam logic hauv qabcurcuminthiabresveratroltxawv heev.

• Xav taucurcumintxuas ntxiv loj hlob hauv kev lag luam Esxias thiab North American, nrog rau cov ntawv thov kev sib koom ua ke kev noj qab haus huv, kev tswj kev mob thiab kev noj zaub mov kis las. Kev yuav khoom tsom ntau dua rau qhov muaj zog, ruaj khov thiab tswj tus nqi.
• ResveratrolLub sijhawm no, tuav txoj haujlwm tseem ceeb hauv cov khoom noj khoom haus zoo tshaj plaws ntawm Tebchaws Europe thiab North America. Nws yog siv dav hauv kev tiv thaiv- kev laus, kev noj qab haus huv ntawm lub plawv, thiab "kev laus noj qab haus huv" cov khoom, nrog rau kev txiav txim siab yuav muab ntau dua rau kev ua raws li kev ua raws cai, purity, thiab kev tshawb fawb pom zoo.

Los ntawm B2B foundations,curcuminleans ntawm kev ua "functionally defined, loj-scale daim ntawv thov muaj", thaumresveratrolyog ntau dua ntawm "tus nqi siab- ntxiv, tswv yim-tsav khoom".

Zuag qhia tag nrho,curcuminthiabresveratroltsis sawv cev rau kev sib tw ua haujlwm nrog kev cuam tshuam sib tshooj, tab sis theej embody nyias txoj hauv kev rau kev cuam tshuam kev noj qab haus huv.Curcuminyog qhov zoo dua rau cov khoom lag luam tsom rau kev tswj kev mob, kev noj qab haus huv ntawm kev sib koom tes, thiab kev txhim kho kev ua haujlwm, whilstresveratrolua kom zoo dua nrog cov khoom lag luam zoo tshaj plaws uas hais txog kev noj qab haus huv ntawm cellular, kev tswj hwm cov metabolism, thiab tiv thaiv - cov ntsiab lus kev laus. Rau cov kws tshaj lij kev muag khoom thiab pab pawg R & D, tus yuam sij rau kev xaiv cov khoom xyaw polyphenolic no nyob rau hauv kom meej meej lub ntsiab lus thov ntawm cov khoom, ua ke nrog bioavailability kev daws teeb meem thiab lub hom phiaj kev nyiam ua lag luam.

Yog xav paub ntxiv txogcov ntaub ntawv khoom, txuas nrog Serrisha los ntawm APPCHEM. (Email:cwj@appchem.cn; +86-138-0919-0407)

Kev siv

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