Dab tsi txiv apples siab hauv phloretin?

Phloretin tau dhau los ua cov khoom muaj hnub qub sai sai hauv kev lag luam tshuaj pleev ib ce, khoom noj khoom haus, thiab tshuaj vim nws muaj zog antioxidant, tiv thaiv - mob, thiab tiv thaiv - kev laus muaj peev xwm. Txawm li cas los xij, rau cov neeg yuav khoom raw khoom thiab cov neeg tsim khoom, cov lus nug tseem ceeb yog: peb yuav tsum xaiv cov khoom siv li cas, thiab cov txiv apples twg muaj ntau dua?Phloretincov ntsiab lus?

Ua ntej sib tham txog cov ntsiab lus, peb yuav tsum xub qhia meej ob feem ntau hais tab sis yooj yim to taub cov ntsiab lus: Phloretin thiab Phloridzin.

Phloridzin: Qhov no yog glycosidic daim ntawv ntawmPhloretin, nyob rau hauv uas ib pawg piam thaj txuas nrog Phloretin molecule. Phloridzin feem ntau pom muaj nyob hauv cov hauv paus hniav, stems, nplooj, thiab tshwj xeeb tshaj yog cov txiv apples. Nws muaj cov dej solubility zoo heev thiab yog lub hauv paus khaws cia thiab kev thauj mus los ntawm hom kev sib xyaw no hauv cov txiv apples.

Phloretin: Qhov no yog daim ntawv aglycone ntawmPhloridzinTom qab tshem tawm glycosides. Ntau cov kev tshawb fawb pharmacological tau pom tias Phloretin yog cov qauv tseem ceeb uas ua rau nws txoj haujlwm tseem ceeb hauv kev lom neeg. Piv txwv li, raws li ntau yam kev tshawb fawb soj ntsuam luam tawm ntawm 2021 thiab 2023,Phloretintau pom cov teebmeem tseem ceeb hauv kev tiv thaiv- qog, tswj cov lus teb inflammatory, tiv thaiv oxidative kev nyuaj siab, thiab ncua kev laus.[1,3,4]

Nyob rau hauv cov nroj tsuag extract kev lag luam, cov txheej txheem ntau lawm ib txwm yog thawj extractPhloridzin, uas yog ntau tshaj nyob rau hauv cov ntsiab lus, los ntawm cov txiv apples, thiab tom qab ntawd hydrolyze thiab tshem tawm cov suab thaj los ntawm biotechnological txhais tau tias xws li enzymatic hydrolysis los yog acid hydrolysis kom tau siab -purity Phloridzin. Yog li ntawd, sib tham txog yam txiv apples muaj peev xwm Phloretin siab yog qhov tseem ceeb sib npaug rau kev tshawb nrhiav hom txiv apple twg muaj ntau.Phloridzincov ntsiab lus.

Nws cov ntsiab lus yog complex, cuam tshuam los ntawm ntau yam xws li ntau yam, qhov chaw loj hlob, sau kom loj hlob, cog ib puag ncig, thiab txawm cia tej yam kev mob. Txawm hais tias qhov tseeb (2022-2024) cov ntawv tshaj tawm kev xeem thiab cov ntaub ntawv pov thawj rau cov khoom lag luam tseem ceeb hauv Suav lag luam, xws li Red Fuji thiab Guoguang, tseem tsis tau tiav, raws li kev tshawb fawb uas twb muaj lawm, peb tuaj yeem kos cov ntsiab lus hauv qab no:
2.1 Core faib cheeb tsam: Peel deb tshaj pulp

Qhov no yog dav lees paub tias yog txoj cai tseem ceeb tshaj plaws hauv kev lag luam thiab kev kawm.Phloretinthiab nws cov glycosides, raws li cov nroj tsuag polyphenols, feem ntau yog synthesized nyob rau hauv epidermal ntaub so ntswg ntawm cov nroj tsuag los tiv thaiv UV hluav taws xob thiab lwm yam pathogen ntxeem tau. Piv txwv li, ib qho kev tshawb fawb qhia meej tias cov ntsiab lus ntawmPhloretinHauv cov kua txiv tev tuaj yeem ncav cuag 80-420 mg / kg, thaum cov ntsiab lus hauv cov txiv hmab txiv ntoo tsuas yog 16-20 mg / kg, nrog qhov sib txawv tseem ceeb ntawm ob.[6] Lwm qhov kev tshuaj ntsuam kuj tau muab qhov zoo sib xws concentration ntau, nrogPhloretinCov ntsiab lus hauv cov kua txiv tev thiab nqaij ntawm 0.06 txog 6.00 mg / 100 g tshiab qhov hnyav (FW), nrog rau feem ntau cov concentrated hauv tev.[5]

2.2 Qhov sib txawv tseem ceeb ntawm ntau yam
Hauv kev tshuaj xyuas ntawm plaub hom txiv apples, cov kws tshawb fawb tau ntsuas qhovPhloretincov ntsiab lus (hauv mg / 100 g) hauv lawv daim tawv nqaij thiab nqaij. Cov txiaj ntsig tau pom tias daim tawv nqaij ntawm Granny Smith (ntsuab apple) thiab Red Delicious (liab nab txiv hmab txiv ntoo / liab marshal) tau nthuav tawm tshwj xeeb tshaj yog kev ua tau zoo.[7] Qhov no txhais tau hais tias ntau yam nrog cov xim tsaus thiab qaub saj yuav feem ntau muaj ntau dua cov tshuaj polyphenolic.
2.3 Qhov cuam tshuam ntawm kev loj hlob: lub peev xwm ntawm cov txiv hmab txiv ntoo unripe

Lub tsub zuj zuj ntawm theem nrab metabolites nyob rau hauv cov nroj tsuag yog ze ze rau lawv txoj kev loj hlob voj voog. Feem ntau, cov txiv hmab txiv ntoo uas tsis paub qab hau ua ke ntau cov phenolic tebchaw los tiv thaiv kev ntxhov siab sab nraud. Yog li ntawd, txiv apples hluas los yog tsis paub tab yuav muaj ntau duaPhloretincov ntsiab lus ntau dua cov txiv hmab txiv ntoo siav.

Rau cov npoj yaig hauv kev lag luam cog qoob loo, txawm hais tias tsis muaj cov lus teb meej rau "qhov twg cov kua txiv hmab txiv ntoo yog qhov zoo tshaj plaws", ua raws li lub tswv yim ntawm "cov tawv nqaij zoo dua li cov nqaij, cov hom tshwj xeeb zoo dua, thiab cov qauv kev lag luam escort", undoubtedly, peb muaj peev xwm nrhiav tau qhov "golden" tivthaiv no (Phloretin) nyob rau hauv txiv apples nyob rau hauv dej hiav txwv xiav no puv lub cib fim.

Yog xav paub ntxiv txogPhloretinthiabPhlorizin, txuas nrog Serrisha los ntawm APPCHEM. (Email:cwj@appchem.cn; +86-138-0919-0407)

Kev siv
[1]Kev dhia dej tob rau hauv lub vaj txiv ntoo ntawm kev noj qab haus huv: Tshawb nrhiav kev tiv thaiv - mob qog noj ntshav thiab tiv thaiv - kev laus muaj peev xwm ntawm cov kua polyphenols. Li-Ching Chen et al. [2025]
[2]Valorization ntawm Kua Pomace: Kev tsim cov Phloretin siv cov kab mob Cellulose-Immobilized -Glycosidase. JM Costa et al. [2022-10-28]
[3]Sustainable Exploitation of Apple Los ntawm-Cov Khoom: Kev Ntsuam Xyuas Rov Qab Los ntawm Kev Tsav Tsheb-Kev Ntsuas Ntsuas Ntsuas Siv Hydrodynamic Cavitation. Tsis tau teev nyob rau hauv cov ntawv nyeem. [2025-05-28]
[4] S. Behzad, A. Sureda et al. "Kev noj qab haus huv los ntawm phloretin: los ntawm chemistry mus rau tshuaj." Phytochemistry Reviews (2017). [2017-03-07]
[5] Kev nyiam ntawm biochemical, anatomical mechanisms, thiab molecular yam hauv enzymatic browning ntawm txiv apples: kev tshuaj xyuas. Mostafa Z. Sultan et al. [2025-02-20]
[6] Pharmacological Aspects thiab Muaj Peev Xwm Siv Phloretin: Kev Ntsuam Xyuas Txheej Txheem. Arokia Vijaya Anand Mariadoss et al. [2019]
[7] C. Remsberg. "Pharmacokinetics, Pharmacodynamics, thiab Formulation Development of Hydrophobic Xenobiotics." (2011). [2011-08-19]