Cov txiv apples puas muaj cov khoom tiv thaiv- laus?

Cov tshuaj tiv thaiv- kev laus ntawm cov txiv apples tsis yog qhov tsis muaj tseeb, thiab nws cov hauv paus hniav nyob hauv ntau yam bioactive compounds uas muaj nyob rau hauv cov txiv hmab txiv ntoo. Cov Cheebtsam no ua haujlwm ua ke los tsim kom muaj kev tiv thaiv ntuj tiv thaiv kev cuam tshuam ntawm lub sijhawm.

1.1 Kua polyphenols: lub ntsiab quab yuam ntawm antioxidants
Apple polyphenols yog lub hauv paus ntawm nws cov khoom tiv thaiv kev laus -. Raws li ntau txoj kev tshawb fawb, kua polyphenols yog ib lub ntsiab lus dav dav rau cov chav kawm ntawm cov sib xyaw ua ke, feem ntau suav nrog flavonoids, phenolic acids, thiab dihydrochalcones.[5] Ntawm lawv, proanthocyanidins yog cov khoom siv ntau tshaj plaws hauv cov kua polyphenols, feem ntau suav txog 71% txog 90% ntawm tag nrho cov ntsiab lus polyphenol.

Cov ntaub ntawv tshwj xeeb uas tsim los ntawm Tebchaws Meskas Lub Tsev Haujlwm Saib Xyuas Kev Ua Liaj Ua Teb (USDA) muab cov ntaub ntawv ntxaws ntxaws rau peb. Piv txwv li, hauv nws "USDA Database for theProanthocyanidinCov ntsiab lus ntawm cov khoom noj uas tau xaiv, "cov ntsiab lus meej ntawm monomers, dimers, trimers, thiab txawm tias polymers ntawm anthocyanins nyob rau hauv ntau hom txiv apples (xws li golden crown, liab nab txiv hmab txiv ntoo, Australian ntsuab txiv apples, thiab lwm yam) thiab lawv cov khoom ua tiav tau sau tseg hauv kev nthuav dav. rho tawm.

Tom qab nkag siab txog cov ntsiab lus tseem ceeb hauv cov txiv apples, peb yuav tsum tshawb nrhiav ntxiv seb lawv ua li cas los tiv thaiv - kev laus ntawm cov qib cellular thiab molecular.

2.1 Muaj zog dawb radical scavenging muaj peev xwm
Qhov "dawb radical txoj kev xav" ntawm kev laus qhia tias ntau dhau dawb radicals tsim thaum lub sij hawm lub cev metabolic dab tuaj yeem tua cell membranes, proteins, thiab DNA, ua rau cell puas thiab ua hauj lwm poob, yog li ua rau kev laus.Kua polyphenolsthiab vitamin C neutralize cov tsis ruaj tsis khov dawb radicals los ntawm kev muab cov electrons, yog li thaiv lawv cov kev cuam tshuam ntawm cov tshuaj tiv thaiv kab mob.[4] Ntau qhov kev tshawb fawb hauv vitro tau lees paub qhov zoo tshaj plaws antioxidant kev ua ntawm cov kua extracts siv txoj kev xws li DPPH thiab ABTS.

2.2 Tiv thaiv thiab qhib cov qia hlwb
Nyob rau hauv xyoo tas los no, cog stem cell technology tau dhau los ua lub ntsiab lus kub hauv kev lag luam tshuaj pleev ib ce. Ntawm lawv, qia cell extracts muab los ntawm ib tug ancient Swiss txiv apples, "Uttwiler Spätleuber," tau nyiam heev. Hom txiv apple no muaj npe nrov rau nws ultra{2}} muaj peev xwm khaws cia ntev. Kev tshawb fawb tau pom tias cov qia cell extract ntawm cov kua no tuaj yeem tiv thaiv qhov tseem ceeb ntawm tib neeg cov tawv nqaij qia hlwb thiab ncua lawv txoj kev laus.[3] Daim ntawv tshaj tawm kev soj ntsuam ntawm 20 tus poj niam tau hais tias tom qab siv cov tshuaj nplaum uas muaj cov extract rau plaub lub lis piam, qhov tob ntawm tus nplaig taw tau txo qis los ntawm qhov nruab nrab ntawm 8%, thiab tom qab yim lub lis piam, nws raug txo los ntawm 15%. Qhov no qhia tau hais tias txiv applestem cell extract ua tiav los tiv thaiv- cov teebmeem kev laus ntawm cov hauv paus hniav los ntawm kev tswj cov tawv nqaij tus kheej lub peev xwm.

2.3 inhibit qhov kev ua ntawm cov enzymes tseem ceeb aging
Lub elasticity ntawm daim tawv nqaij tsuas yog nyob ntawm elastin nyob rau hauv lub dermis txheej. Elastase yog ib qho enzyme uas tuaj yeem degrade elastin, thiab nws cov kev ua ub no nce nrog lub hnub nyoog, ua rau cov tawv nqaij sagging thiab wrinkles. Ib txoj kev tshawb fawb txog qhov tshwj xeeb Italian ntau yam 'Annurca Apple' tau coj cov txiaj ntsig zoo siab. Kev tshawb fawb tau pom tias Annurca Apple Oleolite (AAO) tuaj yeem cuam tshuam kev ua haujlwm ntawm elastase hauv vitro thiab hauv vivo kev sim, yog li tiv thaiv elastin thiab txhim kho daim tawv nqaij elasticity thiab dej tuav lub peev xwm.[6]

Kev tshawb fawb theoretical thiab kev siv tshuab tau pleev xim rau lub neej yav tom ntej rau peb, tab sis rau cov ntawv thov kev lag luam nruj, cov pov thawj soj ntsuam los ntawm tib neeg yog qhov kawg 'tus qauv kub'.

3.1 Cov teebmeem tseem ceeb ntawm daim ntawv thov hauv zos
Tam sim no, cov ntaub ntawv pov thawj kho mob ntawm cov ntawv thov hauv zos ntawmtxiv apple extractyog qhov ntau concentrated thiab meej.

Kev txhim kho Wrinkle: Raws li tau hais ua ntej, Swiss kua qia cell extract tau pom tseeb qhov muaj txiaj ntsig zoo hauv kev txo qis qhov tob.
Cov tawv nqaij ceev thiab elasticity nce ntxiv: Kev tshawb fawb tib neeg ntawm Anurka kua polyphenol extract, luam tawm xyoo 2023, tsim nyog mloog. Txoj kev tshawb no nrhiav 32 tus poj niam tuaj koom, thiab tom qab siv cov khoom lag luam cuam tshuam rau 28 hnub, kev ntsuas ntsuas tau pom tias 78% ntawm cov neeg koom tau muaj qhov nce ntawm cov tawv nqaij ntom ntom, thiab 67% ntawm cov neeg koom tau muaj qhov tseem ceeb hauv qhov nruab nrab ntawm daim tawv nqaij elasticity (p<0.05).
Moisturizing thiab Barrier Function: Ib txoj kev tshawb fawb kuj pom tau tias cov tshuaj pleev ib ce muaj cov tsiaj qustxiv apples extracttuaj yeem ua kom cov tawv nqaij muaj peev xwm ua kom muaj zog, qhia tau hais tias qhov kev ua haujlwm tsis zoo thiab kev muaj peev xwm moisturizing ntawm stratum corneum yog txhim kho.
3.2 Cov khoom noj hauv qhov ncauj: muaj peev xwm thiab cov kev sib tw ua ke
Kev tshawb fawb ntawm qhov ncauj txiv apple extract raws li "sab hauv- tawm" los tiv thaiv- txoj kev laus tseem tab tom tshawb nrhiav. Ib qho randomized, ob npaug - dig muag, placebo- tswj kev sim tshuaj tau sau npe rau kev kho mob ntawm cov poj niam noj qab haus huv cov tawv nqaij mob nrogpolyphenol txiv applecov tshuaj ntxiv, qhia tias kev tshawb fawb hauv daim teb no tab tom mus rau kev tsim qauv. Txawm li cas los xij, qee qhov kev tshuaj xyuas thiab meta- kev tshuaj ntsuam kuj tau taw qhia tias tam sim no tsis muaj kev tshawb fawb txog kev txhim kho cov txiaj ntsig ntawm cov txiv hmab txiv ntoo hauv qhov ncauj lossis lawv cov extracts ntawm daim tawv nqaij wrinkles thiab elasticity, nrog siab heterogeneity ntawm cov kev tshawb fawb thiab feem ntau me me piv txwv.[2] Tsis tas li ntawd, hauv qee qhov kev tshawb fawb,txiv apple extractyog siv los ua ib feem ntawm cov qauv sib xyaw, ua rau nws nyuaj rau kev ntsuas nws qhov kev ua tau zoo ib leeg xwb.[1] Qhov no qhia tau hais tias cov tshuaj tiv thaiv -kev laus ntawm qhov ncauj cov kua txiv extract tseem yuav tsum tau siab dua -zoo, loj- teev randomized tswj kev sim (RCTs) kom paub meej.

Yog xav paub ntxiv txogpolyphenols ntawm txiv apples, txuas nrog Serrisha los ntawm APPCHEM. (Email:cwj@appchem.cn; +86-138-0919-0407)

Kev siv
[1] Cov txiaj ntsig ntawm cov tshuaj ntxiv uas muaj Silybum marianum extract, soy extract, collagen peptide, bifidobacteria, thiab kua extract ntawm daim tawv nqaij: Ib qho placebo randomized - tswj, ob npaug - qhov muag tsis pom, pab pawg sib piv cov kev tshawb fawb soj ntsuam.. Yuri Ishii li al. [2016-06-24]
[2] Haoying Li, Lu Wang et al. "Qhov cuam tshuam ntawm qhov ncauj noj cov txiv hmab txiv ntoo lossis txiv hmab txiv ntoo extract ntawm daim tawv nqaij laus hauv cov neeg laus noj qab haus huv: kev tshuaj xyuas thiab Meta- kev tshuaj xyuas ntawm cov kev sim tshuaj ntsuam xyuas." Frontiers in Nutrition (2023). [2023-08-04]
[3] Ewelina Rostkowska, E. Poleszak et al. "Dermatological Management ntawm Aged Skin." Tshuaj pleev ib ce (2023). [2023-03-27]
[4] TECHNOLOGINIŲ PRIEMONIŲ IR BIOLOGINIŲ VEIKSNIŲ INTENSYVIUOSE OBELŲ (MALUS × DOMESTICA BORKH.) SODUOSE ĮTAKA VAISIŲ KOKYBEI. Jonas Viškelis [2018-10-15]
[5] USDA Database rau Flavonoid Cov Ntsiab Lus ntawm Cov Khoom Noj Xaiv Tso Tawm 3.1. Seema Bhagwat et al. [2013-05]
[6] 皮膚のアンチエイジング成分として期待されるアンヌルカ(Malus pumila Miller cv. Annurca)リンゴオレオライト: 南イタリアで実施された in vitro アッセイと RCTの結果から. 南イタリアのフェデリコ 2 世ナポリ大学薬学部(Department of Pharmacy, University of Naples Federico II [2,3]).[2024-01-06]
[7] USDA Database rau Proanthocyanidin Cov ntsiab lus ntawm Cov Khoom Noj Xaiv Tso Tawm 2. Seema Bhagwat li al.[2015-09]